Sm-a-actin

Webb15 jan. 1992 · Addition of sequence between positions −151 and −257 (p257CAT) resulted in a 7-fold increase in chloramphenicol acetyltransferase activity over that of p151CAT in rat SMC, but not in chicken SMC. A genomic clone encoding the rat smooth muscle alpha-actin gene was isolated, and the 5'-flanking region was partially characterized. Webba decrease in expression of SM-a-actin and increases in non-muscle b-actin expression (5). It is presumed that modulation of VSMC phenotype is me-diated through activation of specific signal transduction path-ways that act on transcription factors. In cultured VSMC, increases in SM-a-actin expression are observed in response to specific agonists.

Pathology Outlines - Actin, alpha smooth muscle type

WebbOur Alpha-Smooth Muscle Actin monoclonal, polyclonal, recombinant monoclonal, cocktail and recombinant polyclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to Alpha-Smooth Muscle Actin. WebbThe cell extracts were analyzed by Western blotting with antibodies against SM-a-actin, SRF, Smad2, Smad4, or b-actin as indicated. (B) Serumstarved human lung fibroblasts … how do i use chatgpt api https://drntrucking.com

Characterization of an E-boxâ Dependent cis Element in the …

WebbThe smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is … Webb14 jan. 2024 · The smooth muscle (SMA) or actin antibody test is primarily ordered along with antinuclear antibodies (ANA) and liver kidney microsomal type 1 (LKM-1) antibodies … WebbPulmonary lymphangioleiomyomatosis (LAM) is a rare genetic disease characterized by neoplastic growth of atypical smooth muscle-like LAM cells, destruction of lung parenchyma, obstruction of... how much paint thinner to use

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Category:Actin (Smooth Muscle) Antibody (Concentrate) Agilent

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Sm-a-actin

ACTB actin beta [Homo sapiens (human)] - Gene - NCBI

WebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast … WebbSM a-actin, SM myosin heavy chain (MHC), and h1 calponin. However, induction of SM a-actin by TGF-bis not restricted to SMCs. A study by Shah et al4 demonstrated that TGF-b stimulated differentiation of neural crest cells into SMCs or SMC-like cells based on morphological criteria and the induction of SM a-actin and h1 calponin. Of particular

Sm-a-actin

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WebbStress may directly activate transcription of the α-SM actin gene, since application of force across integrin binding sites has been shown to up-regulate α-SM actin promoter activity. 52 As mentioned above, mechanical force alone is not generally sufficient to induce myofibroblast differentiation and other factors are needed to act in concert, specifically …

Webbof SM a-actin expression involves a complex interaction of multiple positive and negative cis elements that act in a cell-type specific fashion.10–16 For example, a 547 bp SM a-actin promoter/CAT construct (p547CAT) had high activ-ity in cultured SMCs and in L6 skeletal myotubes, which are cell types that express SM a-actin in culture ... WebbAlpha smooth muscle actin antibody (ab5694) stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also …

ACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA) is often used as a marker of myofibroblast formation. Studies have shown that ACTA2 is associated with TGF-β pathway that enhances contractile properties of hepatic stellate cells leading to liver fibrosis and cirrhosis . Visa mer ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a Visa mer • Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639. S2CID Visa mer • GeneReviews/NIH/NCBI/UW entry on Thoracic Aortic Aneurysms and Aortic Dissections • Human ACTA2 genome location and ACTA2 gene details page in the Visa mer WebbActin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells ( PubMed: 29581253 ). Actin exists in both …

Webb3 dec. 2007 · We identified 2 types of migrating cells with distinctive actin filament structures at the migrating front: type I (Figure (Figure5A), 5 A), cells with a large amount of F-actin stress fibers forming lamellum-like protrusions, and type II (Figure (Figure5A), 5 A), cells with a polarized morphology, a ruffling lamellipodium at the leading edge facing the …

Webb22 okt. 2024 · Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We ... how do i use cheats in subnauticaWebb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway . how do i use cheats in gtaWebbalpha-Smooth muscle (alpha-sm) actin, an isoform typical of smooth muscle cells (SMC) and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of … how do i use chatgtpWebb11 apr. 2024 · ACT, Acceptance and Commitment Therapy, är en vidareutveckling av Kognitiv Beteendeterapi (KBT). Metoden går ut på att lära sig att acceptera smärtan och … how do i use chatgpt with edgeWebbin Sm-a-actin content with increasing age were due, in part, to an increase in Sm-a-actin synthesis. However, in SMCs from 90- and 180-day-old rats, the fractional content of Sm-a-actin exceeded its fractional synthesis at a time when total Sm-a-actin content was increas- ing. This suggests that Sm-a-actin turns over more slowly in mature animals. how do i use chatgpt in chinaWebbSee all alpha smooth muscle Actin primary antibodies Description Mouse monoclonal [1A4] to alpha smooth muscle Actin Host species Mouse Tested applications Suitable … how much paint on a rollerWebb1 mars 2003 · We hypothesized that ablation of smooth muscle α-actin (SM α-A), a contractile-cytoskeletal protein expressed in airway smooth muscle (ASM) cells, … how do i use chatgpt through bing