Irf1 molecular weight
WebObjectives: Although it has been reported that Interferon regulatory factor 1 (IRF1) inhibits Mycobacterium tuberculosis (Mtb) infection via inducible nitric oxide synthase (iNOS) in mice, how it counteracts with mycobacterial infection in human remains largely obscure. WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain …
Irf1 molecular weight
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WebMolecular function Cellular component: Biological process ... Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene. ... Body weight: Normal Anxiety: Normal Neurological assessment: Normal Grip strength: Normal Hot plate: Normal Dysmorphology: WebMay 5, 2014 · Cellular & Molecular Immunology - K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade ... Adding weight to this was the observation that SKI-1, ...
WebSep 29, 2024 · Given that IRF-1 is well known to molecularly act downstream of IFN-γ signaling, we also subjected mice lacking IFN-γ to C. rodentium infection. However, compared to control mice, we observed no... WebJun 30, 2016 · Besides CCL2, the transcription factor IRF1, which has proapoptotic activities was significantly upregulated after IL6/sgp80 or OSM stimulation. qRT-PCR revealed a rapid (within 2 hours) and strong (10- to 12-fold) induction of IRF1 mRNA after OSM or IL6/sgp80 stimulation in HeLa and SW756 cells (Fig. 6A; P <0.0001).
• Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S030… • Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S0300-9084(99… WebIRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta …
WebApr 4, 2024 · IRF-1 is an important signaling protein in the interferon pathway. It not only activates gene expression as a transcription factor, but may perpetuate disease by leading to a dysregulated epigenome. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy.
WebUse a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 36 kDa. ICC Use a concentration of 0.5 - 1 µg/ml. IHC-P ... Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer … greenhouse academy stagione 5WebDec 1, 2024 · The predicted molecular weight of the Cf IRF1 protein was approximately 40 kDa. Using the SMART program and NCBI conserved domain search program, the N-terminus of the Cf IRF1 protein was predicted to encode an IRF1 domain, similar to IRF1 family proteins of other species ( Fig. 2 A ). Download : Download high-res image (2MB) fly and windWebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. ... Consistently, molecular function enrichment … greenhouse academy streaming saison 2greenhouse academy streaming vfWebInterferon regulatory factor 1 (IRF1) is a tumor suppressor gene often found downregulated in breast cancers; this low expression correlates with endocrine therapy resistance (Bouker et al., 2004, 2005, 2007; Gu et al., 2002 ). Approximately, 30% of cancerous breast lesions have allelic loss of IRF1 when compared with the adjacent normal breast ... fly anglaisWebIRF1 (Interferon Regulatory Factor 1 (IRF1)) Alternative Name ... Molecular Weight 58.1 kDa UniProt P15314 Pathways Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive ... fly angler onlineWebIRF1-regulated gene expression equipped low-grade PDAC cells with distinctive properties related to antigen presentation and processing as well as responsiveness to IFN stimulation. greenhouse academy trailer