국내 paclitaxel resistance a549

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August undefined, 2024

WebDosis paclitaxel yang diberikan oleh dokter tergantung pada kondisi kesehatan dan luas permukaan tubuh (LPT) pasien. Secara umum, dosis paclitaxel untuk orang dewasa … WebPTX-resistant (A549- and PC-3-PacR) cells were developed to have transient cross-resistance to 5-fluorouracil (PacR/5-FU), docetaxel (PacR/DCT), and cisplatin (PacR/CIS) by culturing PTX-...

Prior acquired resistance to paclitaxel relays diverse

WebThe combination of conventional cytotoxic drugs has been a plausible strategy for overcoming paclitaxel resistance. Herein, we investigated the cytotoxic effects and underlying mechanism of LSS-11, a novel naphthalimide derivative-based topoisomerase inhibitor, in paclitaxel-resistant A549 (A549/T) lung cancer cells. LSS-11 enhanced cell … WebFeb 24, 2024 · Human non-small cell lung cancer cell line (A549), and paclitaxel-resistant A549 (A549/T) cell line was purchased from iCell Biosciences Inc. (Shanghai, China). Both A549/T and A549 cell lines … hope valley nc map

Knockdown of long non-coding RNA KCNQ1OT1 depressed

WebNov 14, 2016 · Human lung cancer A549 cells, A549/PTX (paclitaxel-resistant) cells and A549/DDP (cisplatin-resistant) cells were tested. The resistance to cisplatin or paclitaxel was detected... WebFeb 28, 2024 · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In … long tail business model example

Synergistic Combination of Sodium Aescinate-Stabilized, Polymer …

SphK1 functions downstream of IGF-1 to modulate IGF-1-induced …

http://ir.bjmu.edu.cn/handle/400002259/135151?mode=full WebJun 9, 2024 · Figure 3 B showed that IC50 values for paclitaxel in A549 and A549/PA cells were 1.23 ± 0.14 and 7.03 ± 0.32 μmol/L, respectively, indicating much higher values for A549/PA cells, whose resistance index (RI) was 5.02. A549/PA cells showed more powerful resistance to paclitaxel ( P < 0.05). long tail bobcat picturesWebNov 29, 2024 · Background Cisplatin plus pemetrexed combination therapy is considered the standard treatment for patients with advanced, non-squamous, non-small-cell lung cancer (NSCLC). However, advanced NSCLC has a 5-year survival rate of below 10%, which is mainly due to therapy resistance. We previously showed that the NSCLC cell … long tail business model examples

"WebIn this work, we established paclitaxel-resistant cells (A549-T) from parental cell lines by step-dose selection in vitro. Using methylation chip analysis and transcriptome … " - 국내 paclitaxel resistance a549

국내 paclitaxel resistance a549

A549 – A model for non-small cell lung cancer - Labcorp Drug Develop…

WebMay 25, 2010 · The paclitaxel-resistant A549-Taxol cell line was established as previously reported. Briefly, the cell lines were selected to be paclitaxel resistant by continuous … WebThe cellular uptake, intracellular nanoparticle trajectory, and subsequent cellular events were evaluated after treatment with various PLGA nanocomplexes in human lung cancer A549 cells and A549-derived paclitaxel-resistant A549/T12 cell lines with -tubulin mutation.Results: A549 and A549/T12 cells contain constitutively activated Stat3, and ...

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WebThis study aimed to investigate the effect of apatinib on the reversal of paclitaxel (PTX) resistance in A549 lung cancer cells (A549/PTX) and related mechanisms. Materials … WebJan 24, 2024 · Unlike common chemotherapeutic drugs such as paclitaxel and cisplatin, cancer cells did not develop acquired resistance to COTI-2. Finally, tumor cells resistant to chemotherapeutic agents (cisplatin, paclitaxel, and 5-FUdR) exhibited no or little cross-resistance to COTI-2.

WebSep 7, 2024 · SOX2 regulates paclitaxel resistance of A549 non‑small cell lung cancer cells via promoting transcription of ClC‑3 . Authors Youwei Huang 1 , Xiangyu Wang 1 , … WebAnalysis of Differential Expression Proteins of Paclitaxel-Treated Lung Adenocarcinoma Cell A549 Using Tandem Mass Tag-Based Quantitative Proteomics. Background: Paclitaxel is widely used in the treatment of cancer and has a good effect in the treatment of non-small cell lung cancer. The combination of TMT proteomics and bioinformatics is used ...

WebAbstract Objective To investigate the effect of the SMAC gene on paclitaxel sensitivity and cellular activity in lung adenocarcinoma cells based on the caspase-3/Bcl-2/Bax signaling pathway. Methods A paclitaxel-resistant cell line A549/Taxol was established for lung adenocarcinoma, and the cells were divided into four following groups: pcDNA-NC … WebMay 15, 2024 · A549 resistance to DDP (A549/DDP) was established. Microarray was used to analyze microRNA (miRNA) expression profiles of A549 cells, A549/DDP cells, A549 exosomes, and A549/DDP exosomes. There was a strong correlation of miRNA profiles between exosomes and their maternal cells. A total of 11 miRNAs were significantly …

WebSilencing USP14 increased the tumor antagonistic action of DDP in A549 cisplatin-resistant (A549/DDP) cells, while USP14 overexpression decreased the antagonist effects. ... and lymphoma. 29 He et al. developed two AMs that selectively bind to two glycoproteins on the surface of a paclitaxel-resistant ovarian carcinoma cell line with high ...

WebJan 2, 2024 · Farmakokinetik. Paclitaxel dilaporkan memiliki farmakokinetik nonlinear, terutama jika diberikan melebihi 3 jam. Konsentrasi plasma maksimum dan area under … longtail butterflyhttp://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2024.22.1114 hope valley netball clubWebCell culture and establishment of paclitaxel-resistant A549-Taxol The paclitaxel-resistant A549-Taxol cell line was estab-lished as previously reported. Brieﬂy, the cell lines were … hope valley north carolinaWebMar 1, 2024 · Paclitaxel (PTX) is a common antineoplastic drug whose functionality is often restricted by drug resistance. Solute carrier organic anion transporter family member … hope valley peak district national parkWebPaclitaxel resistance in human A549, DU-145, H1299, H1993, H292, H358, H460, LNCaP clone FGC, and PC-3 cell lines and mouse LLC1 cell line and epothilone B resistance in … hope valley lutheran homesWebMar 1, 2024 · A549 cells were exposed to PTX at the concentrations of 20 nM, 40 nM, 50 nM, 70 nM, 90 nM, 100 nM for 2 weeks each concentration. 4 months were taken to … long tail calligraphy fontWebA549 or paclitaxel-resistant A549 cells were seeded at 3000 cells/well in 96-well plates and cultured overnight. SphK1 specific inhibitor SKI-II, Cisplatin or paclitaxel were then added to the wells at varying concentrations. The cells were further cultured for additional 3 … hopevalleyprintables.wordpress.com